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本刊由卫生部主管，山东大学主办的国家级学术性期刊，国内外公开发行，被确定为外科学类，肿瘤学类，医药卫生类核心期刊。以从事普通外科的临床工作者、科研人员和研究生为主要读者对象。报道普通外科领域内最新学术动态和进展、临床实践经验和原创性科研成果，以及与临床密切结合的基础理论研究。
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首页>中国现代普通外科进展杂志
- 杂志名称：中国现代普通外科进展杂志
- 主管单位：中华人民共和国教育部
- 主办单位：山东大学
- 国际刊号：1009-9905
- 国内刊号：37-1369/R
- 出版周期：月刊
期刊荣誉：华东地区优秀期刊期刊收录：万方收录(中), CA 化学文摘(美), 上海图书馆馆藏, 国家图书馆馆藏, 知网收录(中), 统计源核心期刊(中国科技论文核心期刊), 维普收录(中)
王昆华；廖吉勋；李达科；廖祥伟；秦明和
关键词：pancreatitis, microcirculation, Thromboxane A2, Prostaglandins F
摘要：Objective :To study the pathogenesis of acute severe pancreatitis(ASP).Methods: Minic models of rats with ASP were replicated. Retrograde injection of 3.5% sodium traurodeoxideocholic acid into them via pancreatic-bile duct with the catheters to abdominal aorta and peripheral blood vessel was performed. Then the concentrations of plasmic TXA2 and PGF1α were measured by RIA. The changes of pancreatic morphology were observed by macroscopy and microscopy, and microcirculation observed by intravital microscopy. Results :The concentration of plasmic TXA2 is rapidly deereased in abdomi- nal aorta perfusion. The changes of pancreatic morphology and microcirculation and the concentration of plasmic TXA2 is significantly different(P ＜ 0.01). Conclusion: The ob- stacle of pancreatic microcirculation is the cause and effect.
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